Akira is a normal high school boy, but he nevertheless impulsively licks some drool left by the mysterious transfer student Mikoto. The next day he falls asleep with an inexplicable fever. After five days Mikoto suddenly comes to visit, and makes him consume her drool. The fever instantly vanishes, and Mikoto explains that he's suffering from "love sickness." She can transmit emotions through her drool, and the two of them are now bound together.
Detective Scott Turner has three days left in the local police department before he moves to a bigger city to get some 'real' cases—not just misdemeanors. When Amos Reed is murdered, Scott sets himself on the case, but the closest thing to a witness to the murder is Reed's dog, Hooch, which Scott has to take care of—to avoid Hooch being 'put to sleep'.
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